Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19639251 | 0.92 | HDAC1 (0.52) | HDAC1BCL2BCHEPTPN1SMN1; SMN2 | |
| SCHEMBL26633557 | 0.85 | FFAR1 (0.45) | HDAC1BCL2BCHEPTPN1SMN1; SMN2 | |
| SCHEMBL6243210 | 0.84 | HDAC1 (0.54) | HDAC1BCL2BCHESMN1; SMN2NPC1 | |
| SCHEMBL19639305 | 0.82 | GAA (0.53) | HDAC1BCL2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL19639378 | 0.81 | GID4 (0.54) | HDAC1SMN1; SMN2NPC1RAB9AMAOB | |
| SCHEMBL17902822 | 0.81 | CA1 (0.51) | HDAC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL19651943 | 0.81 | CA1 (0.51) | HDAC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL596575 | 0.78 | HDAC1 (0.67) | HDAC1BCHESMN1; SMN2NPC1RAB9A | |
| SCHEMBL22416647 | 0.78 | ADAMTS4 (0.46) | HDAC1BCL2PTPN1SMN1; SMN2NPC1 | |
| SCHEMBL19639292 | 0.78 | TSHR (0.44) | HDAC1SMN1; SMN2CA1MAOBADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213728-A1 | SUBSTITUTED ARYL ESTERS OF COUMARIN-3-CARBOXYLIC ACID AND THEIR USE AS HOST CELL PROTEASES INHIBITORS | Université de Liège (BE) | 2023-11-09 | — | — | WO | disclosed |