Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 12/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GCGR | P47871 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2663435 | 0.84 | CA1 (0.52) | SIGMAR1TMEM97HDAC8HDAC6CA1 | |
| SCHEMBL13799956 | 0.82 | MCHR1 (0.51) | SIGMAR1TMEM97ACKR3CA1CA2 | |
| SCHEMBL3199550 | 0.82 | GCGR (0.58) | CA1CA2MAPK1GCGR | |
| SCHEMBL13800570 | 0.80 | CA1 (0.50) | SIGMAR1TMEM97HDAC1ACKR3HDAC6 | |
| SCHEMBL9717434 | 0.79 | MAPK1 (0.71) | HDAC8HDAC6CA1CA2MAPK1 | |
| SCHEMBL3195210 | 0.79 | L3MBTL1 (0.61) | SIGMAR1TMEM97HDAC8HDAC6CA1 | |
| SCHEMBL24590556 | 0.78 | KMT2A (0.54) | SIGMAR1TMEM97HDAC1ACKR3HDAC6 | |
| SCHEMBL13800502 | 0.78 | CA1 (0.45) | SIGMAR1TMEM97ACKR3CA1CA2 | |
| SCHEMBL15071635 | 0.77 | FFAR1 (0.53) | HDAC1CA1CA2 | |
| SCHEMBL9072937 | 0.77 | CA1 (0.52) | HDAC1HDAC8HDAC6CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |