Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | CA1 | P00915 | 3/20 | 0.71 |
| ▸ | CA2 | P00918 | 3/20 | 0.71 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.58 |
| ▸ | CTSG | P08311 | 1/20 | 0.58 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.58 |
| ▸ | CMA1 | P23946 | 1/20 | 0.58 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.56 |
| ▸ | NME4 | O00746 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | GCDH | Q92947 | 1/20 | 0.56 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3211210 | 0.92 | CA1 (0.63) | MAPK1CA1CA2PRSS1CTSG | |
| Betamipron SCHEMBL4498475 | 0.91 | PRSS1 (0.70) | MAPK1CA1CA2PRSS1CTSG | |
| Betamipron SCHEMBL605899 | 0.91 | PRSS1 (0.70) | MAPK1CA1CA2PRSS1CTSG | |
| SCHEMBL8879067 | 0.90 | CA1 (0.61) | MAPK1CA1CA2PRSS1CTSG | |
| SCHEMBL5625471 | 0.90 | CYP1A2 (0.66) | MAPK1CA1CA2CYP1A2CYP2C19 | |
| SCHEMBL17946072 | 0.90 | CA1 (0.61) | MAPK1CA1CA2LMNAL3MBTL1 | |
| SCHEMBL279993 | 0.90 | LMNA (0.71) | MAPK1CA1CA2CYP1A2CYP2C9 | |
| SCHEMBL2644934 | 0.90 | CA1 (0.61) | MAPK1CA1CA2PRSS1CTSG | |
| SCHEMBL1520329 | 0.90 | NPC1 (0.63) | MAPK1CA1CA2SIRT5KDM4E | |
| SCHEMBL130343 | 0.90 | KDM4E (0.68) | MAPK1CA1CA2PRSS1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562203-B1 | POLYAMIDE COMPOUND | MITSUBISHI GAS CHEMICAL CO (JP) | 2015-09-30 | — | — | EP | disclosed |
| US-8492504-B2 | Catalytic depolymerization of polymers containing electrophilic linkages using nucleophilic reagents | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-07-23 | — | — | US | disclosed |
| US-8492504-B2 | Catalytic depolymerization of polymers containing electrophilic linkages using nucleophilic reagents | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-07-23 | — | — | US | disclosed |
| US-20120302781-A1 | Catalytic Depolymerization of Polymers Containing Electrophilic Linkages Using Nucleophilic Reagents | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-11-29 | — | — | US | disclosed |
| US-20120302781-A1 | Catalytic Depolymerization of Polymers Containing Electrophilic Linkages Using Nucleophilic Reagents | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-11-29 | — | — | US | disclosed |
| US-8309618-B2 | Catalytic depolymerization of polymers containing electrophilic linkages using nucleophilic reagents | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-11-13 | — | — | US | disclosed |
| US-8309618-B2 | Catalytic depolymerization of polymers containing electrophilic linkages using nucleophilic reagents | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-11-13 | — | — | US | disclosed |
| US-20110004014-A1 | Catalytic Depolymerization of Polymers Containing Electrophilic Linkages Using Nucleophilic Reagents | NATIONAL SCIENCE FOUNDATION | 2011-01-06 | — | — | US | disclosed |
| US-20110004014-A1 | Catalytic Depolymerization of Polymers Containing Electrophilic Linkages Using Nucleophilic Reagents | NATIONAL SCIENCE FOUNDATION | 2011-01-06 | — | — | US | disclosed |
| US-5086104-A | Mixture of thermoplastic resin, elastomer and amide compound, excellent toughtness, heat resistance and durability | POLYPLASTICS CO., LTD. (JP) | 1992-02-04 | — | — | US | disclosed |
| US-4556697-A | Alternating copolyamide prepared on a polymer matrix | THE STANDARD OIL COMPANY (US) | 1985-12-03 | — | — | US | disclosed |
| US-4429109-A | Polyamides with high glass transition temperatures prepared from N,N'-terephthaloyldi-beta-alanine and a diamine | STANDARD OIL COMPANY (US) | 1984-01-31 | — | — | US | disclosed |
| US-4429109-A | Polyamides with high glass transition temperatures prepared from N,N'-terephthaloyldi-beta-alanine and a diamine | STANDARD OIL COMPANY (US) | 1984-01-31 | — | — | US | disclosed |
| US-4429109-A | Polyamides with high glass transition temperatures prepared from N,N'-terephthaloyldi-beta-alanine and a diamine | STANDARD OIL COMPANY (US) | 1984-01-31 | — | — | US | disclosed |
| US-4393192-A | Crystalline copolymers prepared from N,N'-terephthaloyldi-beta-alanine and a glycol | THE STANDARD OIL COMPANY (US) | 1983-07-12 | — | — | US | disclosed |
| US-4393192-A | Crystalline copolymers prepared from N,N'-terephthaloyldi-beta-alanine and a glycol | THE STANDARD OIL COMPANY (US) | 1983-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302781-A1 | Catalytic Depolymerization of Polymers Containing Electrophilic Linkages Using Nucleophilic Reagents | UNG, GDA, MPG | MAPK1 3314/4885CA1 2299/4885CA2 1790/4885 |
| US-20110004014-A1 | Catalytic Depolymerization of Polymers Containing Electrophilic Linkages Using Nucleophilic Reagents | UNG, GDA, MPG | MAPK1 3314/4885CA1 2299/4885CA2 1790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.