Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | B4GALT1 | P15291 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24239904 | 0.91 | LMNA (0.52) | LMNASMN1; SMN2KMT2APOLBMEN1 | |
| SCHEMBL24294654 | 0.90 | LMNA (0.50) | LMNASMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL24239944 | 0.88 | LMNA (0.61) | LMNASMN1; SMN2KMT2APOLBMAPT | |
| SCHEMBL24239907 | 0.88 | LMNA (0.61) | LMNASMN1; SMN2KMT2APOLBMAPT | |
| SCHEMBL19935063 | 0.88 | LMNA (0.61) | LMNASMN1; SMN2KMT2APOLBMAPT | |
| SCHEMBL31400136 | 0.88 | LMNA (0.61) | LMNASMN1; SMN2KMT2APOLBMAPT | |
| SCHEMBL30980624 | 0.87 | MAPK1 (0.52) | LMNASMN1; SMN2KMT2APOLBMEN1 | |
| SCHEMBL20985069 | 0.86 | MAPK1 (0.53) | LMNASMN1; SMN2KMT2APOLBMEN1 | |
| SCHEMBL30980644 | 0.84 | LMNA (0.59) | LMNASMN1; SMN2KMT2APOLBMAPT | |
| SCHEMBL20985072 | 0.82 | LMNA (0.65) | LMNASMN1; SMN2KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215306-A1 | PROCESSES FOR MAKING NAG-25, A CARBOHYDRATE TARGETING MOIETY, AND ITS INTERMEDIATES | AMGEN INC. (US) | 2023-11-09 | — | — | WO | disclosed |