Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | B4GALT1 | P15291 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.44 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.44 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.44 |
| ▸ | HRAS | P01112 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24239904 | 0.96 | LMNA (0.52) | MAPK1LMNASMN1; SMN2B4GALT1MEN1 | |
| SCHEMBL24699869 | 0.92 | MAPK1 (0.57) | MAPK1B4GALT1MEN1KMT2ALGALS8 | |
| SCHEMBL22855653 | 0.92 | MAPK1 (0.57) | MAPK1B4GALT1MEN1KMT2ALGALS8 | |
| SCHEMBL20985069 | 0.92 | MAPK1 (0.53) | MAPK1LMNASMN1; SMN2B4GALT1MEN1 | |
| SCHEMBL17283441 | 0.91 | MAPK1 (0.60) | MAPK1B4GALT1MEN1KMT2ALGALS8 | |
| SCHEMBL24294654 | 0.89 | LMNA (0.50) | MAPK1LMNASMN1; SMN2B4GALT1MEN1 | |
| SCHEMBL26634406 | 0.87 | LMNA (0.50) | MAPK1LMNASMN1; SMN2B4GALT1MEN1 | |
| SCHEMBL2003046 | 0.86 | LMNA (0.50) | MAPK1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL15499416 | 0.85 | MAPK1 (0.55) | MAPK1B4GALT1MEN1KMT2ALGALS8 | |
| SCHEMBL18875811 | 0.85 | MAPK1 (0.67) | MAPK1B4GALT1MEN1KMT2ALGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651902-A2 | ASGPR BINDING COMPOUNDS AND CONJUGATES | Lycia Therapeutics, Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2025035040-A1 | LYSOSOMAL TARGETING BIFUNCTIONAL MOLECULES FOR DEGRADATION OF MUSCLE-SPECIFIC KINASE AUTOANTIBODIES | LYCIA THERAPEUTICS, INC. (US) | 2025-02-13 | — | — | WO | disclosed |
| WO-2024155747-A2 | ASGPR BINDING COMPOUNDS AND CONJUGATES | LYCIA THERAPEUTICS, INC. (US) | 2024-07-25 | — | — | WO | disclosed |