Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 4/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30540196 | 1.00 | ALOX5AP (0.39) | ALOX5APFEN1SRCALDH1A1KDM4E | |
| SCHEMBL26635226 | 0.85 | ALOX5AP (0.43) | ALOX5APFEN1ALDH1A1KDM4EERN1 | |
| SCHEMBL30540236 | 0.85 | ALOX5AP (0.43) | ALOX5APFEN1ALDH1A1KDM4EERN1 | |
| SCHEMBL30540206 | 0.84 | ERN1 (0.41) | ALOX5APFEN1ERN1 | |
| SCHEMBL26635272 | 0.84 | ERN1 (0.41) | ALOX5APFEN1ERN1 | |
| SCHEMBL30540254 | 0.84 | FEN1 (0.54) | ALOX5APFEN1ALDH1A1 | |
| SCHEMBL26635214 | 0.84 | FEN1 (0.54) | ALOX5APFEN1ALDH1A1 | |
| SCHEMBL30540244 | 0.82 | XDH (0.46) | ALOX5APFEN1ALDH1A1ERN1PDK2 | |
| SCHEMBL26635161 | 0.82 | XDH (0.46) | ALOX5APFEN1ALDH1A1ERN1PDK2 | |
| SCHEMBL30540245 | 0.81 | KCNH2 (0.43) | ALOX5APFEN1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023208151-A1 | USP INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION | 北京华森英诺生物科技有限公司 | 2023-11-02 | — | — | WO | disclosed |
| CN-116621778-A | USP inhibitor, preparation method and application thereof | 北京华森英诺生物科技有限公司 | 2023-08-22 | — | — | CN | disclosed |