SCHEMBL26635331

SCHEMBL26635331

CCCCCCCCCCCCOc1cccc(I)c1

nearest known ligand 0.65

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.65
SMPD1 P17405 3/20 0.57
PLA2G4B P0C869 2/20 0.54
THRA P10827 1/20 0.52
THRB P10828 1/20 0.52
LTA4H P09960 1/20 0.51
GGPS1 O95749 2/20 0.50
KMT2A Q03164 1/20 0.50
NR5A1 Q13285 1/20 0.49
NR1H4 Q96RI1 1/20 0.48
GPBAR1 Q8TDU6 1/20 0.48
PRSS1 P07477 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2352668 1.00 TSHR (0.65) TSHRSMPD1PLA2G4BTHRATHRB
SCHEMBL25169961 1.00 TSHR (0.65) TSHRSMPD1PLA2G4BTHRATHRB
SCHEMBL25167623 1.00 TSHR (0.65) TSHRSMPD1PLA2G4BTHRATHRB
SCHEMBL4187873 0.93 TSHR (0.54) TSHRSMPD1PLA2G4BTHRBLTA4H
SCHEMBL8552100 0.87 KMT2A (0.59) TSHRSMPD1KMT2ANR1H4GPBAR1
SCHEMBL6677146 0.87 TSHR (0.76) TSHRSMPD1PLA2G4BTHRATHRB
SCHEMBL17138169 0.87 TSHR (0.76) TSHRSMPD1PLA2G4BTHRATHRB
SCHEMBL4208924 0.87 TSHR (0.76) TSHRSMPD1PLA2G4BTHRATHRB
SCHEMBL3905859 0.87 TSHR (0.76) TSHRSMPD1PLA2G4BTHRATHRB
SCHEMBL16699620 0.87 TSHR (0.76) TSHRSMPD1PLA2G4BTHRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353867-A1 Substituted Pyridine-2,6-Bis(Phenylenephenolate) Complexes with Enhanced Solubility that are Useful as Catalyst Components for Olefin Polymerization EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-11-20 US disclosed
EP-4519332-A1 SUBSTITUTED PYRIDINE-2,6-BIS (PHENYLENEPHENOLATE) COMPLEXES WITH ENHANCED SOLUBILITY THAT ARE USEFUL AS CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2025-03-12 EP disclosed
WO-2023215695-A1 SUBSTITUTED PYRIDINE-2,6-BIS (PHENYLENEPHENOLATE) COMPLEXES WITH ENHANCED SOLUBILITY THAT ARE USEFUL AS CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-11-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353867-A1 Substituted Pyridine-2,6-Bis(Phenylenephenolate) Complexes with Enhanced Solubility that are Useful as Catalyst Components for Olefin Polymerization HPD, YAP1, PAH TSHR 4771/4885SMPD1 4784/4885PLA2G4B 2074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.