Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 11/20 | 0.63 |
| ▸ | GLP1R | P43220 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4087887 | 0.89 | GCGR (0.52) | GCGRGLP1RHDAC3HDAC1HDAC2 | |
| SCHEMBL4091957 | 0.75 | GCGR (0.64) | GCGRGLP1RHDAC3HDAC1HDAC2 | |
| SCHEMBL2662297 | 0.74 | GCGR (0.54) | GCGRGLP1RHDAC3HDAC1HDAC2 | |
| SCHEMBL2663009 | 0.73 | GCGR (0.79) | GCGRGLP1RHDAC3HDAC1HDAC7 | |
| SCHEMBL13800474 | 0.72 | GCGR (0.61) | GCGRGLP1RHDAC3HDAC1HDAC7 | |
| SCHEMBL2663347 | 0.70 | GCGR (0.56) | GCGRGLP1RHDAC3HDAC1HDAC2 | |
| SCHEMBL2663011 | 0.69 | CXCR3 (0.53) | GCGRGLP1RHDAC1TMEM97SIGMAR1 | |
| SCHEMBL4081595 | 0.68 | GCGR (0.80) | GCGRGLP1RTMEM97SIGMAR1GIPR | |
| SCHEMBL2663201 | 0.68 | GCGR (0.53) | GCGRGLP1RTMEM97SIGMAR1KMT2A | |
| SCHEMBL4926908 | 0.67 | ALDH1A1 (0.51) | MEN1KMT2ABCAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |