SCHEMBL26637240

SCHEMBL26637240

CC(C)(C)C(=O)OCOP(=O)(OC[C@H]1O[C@@](C#N)(c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O)Oc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ TMPRSS2 O15393 1/20 0.43
▸ RNASEL Q05823 2/20 0.32
▸ POLRMT O00411 1/20 0.32
▸ RIPK1 Q13546 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31684063 0.93 TMPRSS2 (0.43) TMPRSS2RNASELPOLRMT
SCHEMBL31684188 0.93 TMPRSS2 (0.43) TMPRSS2RNASELPOLRMT
SCHEMBL30939781 0.93 TMPRSS2 (0.43) TMPRSS2RNASELPOLRMT
SCHEMBL24917155 0.93 TMPRSS2 (0.45) TMPRSS2RNASELPOLRMT
SCHEMBL26637255 0.90 TMPRSS2 (0.41) TMPRSS2RNASELPOLRMT
SCHEMBL30939763 0.89 TMPRSS2 (0.42) TMPRSS2POLRMTRIPK1
SCHEMBL26599239 0.89 TMPRSS2 (0.44) TMPRSS2POLRMTRIPK1
SCHEMBL26651178 0.89 POLRMT (0.33) TMPRSS2RNASELPOLRMTRIPK1
SCHEMBL26637293 0.89 TMPRSS2 (0.41) TMPRSS2POLRMTRIPK1
SCHEMBL30622272 0.89 TMPRSS2 (0.45) TMPRSS2POLRMTRIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230338409-A1 NUCLEOSIDE DRUGS FOR THE TREATMENT OR PREVENTION OF CORONAVIRUS INFECTION AND THEIR USES MIRACURE BIOTECHNOLOGY LTD (CN) 2023-10-26 — — US disclosed
US-20230338409-A1 NUCLEOSIDE DRUGS FOR THE TREATMENT OR PREVENTION OF CORONAVIRUS INFECTION AND THEIR USES MIRACURE BIOTECHNOLOGY LTD (CN) 2023-10-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230338409-A1 NUCLEOSIDE DRUGS FOR THE TREATMENT OR PREVENTION OF CORONAVIRUS INFECTION AND THEIR USES PNP, MTAP, TYMP TMPRSS2 149/4885RNASEL 57/4885POLRMT 210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback