SCHEMBL26637255

SCHEMBL26637255

CC(C)(C)C(=O)OCOP(=O)(OC[C@H]1O[C@@](C#N)(c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O)Oc1cccc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ TMPRSS2 O15393 1/20 0.41
▸ POLRMT O00411 1/20 0.32
▸ BTN3A1 O00481 1/20 0.32
▸ RNASEL Q05823 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26637240 0.90 TMPRSS2 (0.43) TMPRSS2POLRMTRNASEL
SCHEMBL24917155 0.90 TMPRSS2 (0.45) TMPRSS2POLRMTRNASEL
SCHEMBL31684109 0.90 TMPRSS2 (0.40) TMPRSS2POLRMT
SCHEMBL26651233 0.90 POLRMT (0.33) POLRMTBTN3A1RNASEL
SCHEMBL26637298 0.90 TMPRSS2 (0.39) TMPRSS2POLRMT
SCHEMBL26637301 0.90 TMPRSS2 (0.39) TMPRSS2POLRMT
SCHEMBL31684063 0.86 TMPRSS2 (0.43) TMPRSS2POLRMTRNASEL
SCHEMBL30939781 0.86 TMPRSS2 (0.43) TMPRSS2POLRMTRNASEL
SCHEMBL31684188 0.86 TMPRSS2 (0.43) TMPRSS2POLRMTRNASEL
SCHEMBL30921699 0.85 TMPRSS2 (0.39) TMPRSS2POLRMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230338409-A1 NUCLEOSIDE DRUGS FOR THE TREATMENT OR PREVENTION OF CORONAVIRUS INFECTION AND THEIR USES MIRACURE BIOTECHNOLOGY LTD (CN) 2023-10-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230338409-A1 NUCLEOSIDE DRUGS FOR THE TREATMENT OR PREVENTION OF CORONAVIRUS INFECTION AND THEIR USES PNP, MTAP, TYMP TMPRSS2 149/4885POLRMT 210/4885BTN3A1 4775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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