Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26638209 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MEN1GAAKMT2ALMNA | |
| SCHEMBL22805687 | 0.93 | ALDH1A1 (0.56) | ALDH1A1MEN1GAAKMT2ALMNA | |
| SCHEMBL22805239 | 0.93 | ALDH1A1 (0.56) | ALDH1A1MEN1GAAKMT2ALMNA | |
| SCHEMBL22805539 | 0.86 | ALDH1A1 (0.49) | ALDH1A1MEN1GAAKMT2ALMNA | |
| SCHEMBL22805541 | 0.86 | ALDH1A1 (0.49) | ALDH1A1MEN1GAAKMT2ALMNA | |
| SCHEMBL26638223 | 0.82 | LMNA (0.53) | ALDH1A1MEN1GAAKMT2ALMNA | |
| SCHEMBL26638225 | 0.82 | LMNA (0.53) | ALDH1A1MEN1GAAKMT2ALMNA | |
| SCHEMBL26638193 | 0.81 | LMNA (0.45) | ALDH1A1MEN1KMT2ALMNAHPGD | |
| SCHEMBL26638191 | 0.81 | LMNA (0.45) | ALDH1A1MEN1KMT2ALMNAHPGD | |
| SCHEMBL26638240 | 0.79 | LMNA (0.46) | ALDH1A1MEN1GAAKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986873-B9 | 5-[(1S)-1-(4-BROMOPHENOXY)ETHYL]-2H-TETRAZOLE DERIVATIVES AND RELATED COMPOUNDS AS CLC-1 ION CHANNEL INHIBITORS FOR TREATING NEUROMUSCULAR DISORDERS | NMD PHARMA AS (DK) | 2024-05-29 | — | — | EP | disclosed |
| EP-3986873-B1 | 5-[(1S)-1-(4-BROMOPHENOXY)ETHYL]-2H-TETRAZOLE DERIVATIVES AND RELATED COMPOUNDS AS CLC-1 ION CHANNEL INHIBITORS FOR TREATING NEUROMUSCULAR DISORDERS | NMD PHARMA AS (DK) | 2023-11-15 | — | — | EP | disclosed |