Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ATP4A | P20648 | 9/20 | 0.47 |
| ▸ | ATP4B | P51164 | 9/20 | 0.47 |
| ▸ | ATP1A1 | P05023 | 8/20 | 0.47 |
| ▸ | ATP1B1 | P05026 | 8/20 | 0.47 |
| ▸ | ATP1A3 | P13637 | 8/20 | 0.47 |
| ▸ | ATP1B2 | P14415 | 8/20 | 0.47 |
| ▸ | ATP1A2 | P50993 | 8/20 | 0.47 |
| ▸ | ATP1B3 | P54709 | 8/20 | 0.47 |
| ▸ | FXYD2 | P54710 | 8/20 | 0.47 |
| ▸ | ATP1A4 | Q13733 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | WDR5 | P61964 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26765301 | 0.92 | NPC1 (0.48) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2623644 | 0.91 | CYP2C9 (0.48) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6872754 | 0.91 | CYP2C9 (0.48) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5661872 | 0.90 | CYP2C9 (0.47) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23988380 | 0.90 | NPC1 (0.46) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6881741 | 0.90 | NPC1 (0.46) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23988392 | 0.90 | NPC1 (0.46) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| Lansoprazole SCHEMBL5308197 | 0.89 | CYP2C9 (0.62) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23988515 | 0.89 | NPC1 (0.46) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23988597 | 0.89 | NPC1 (0.46) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357261-A1 | ARYL HYDROCARBON RECEPTOR LIGANDS AND THEIR ANALOGUES FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISORDERS | The University of Pittsburgh- of the Commonwealth System of Higher Education | 2023-11-09 | — | — | US | disclosed |
| US-20230357261-A1 | ARYL HYDROCARBON RECEPTOR LIGANDS AND THEIR ANALOGUES FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISORDERS | The University of Pittsburgh- of the Commonwealth System of Higher Education | 2023-11-09 | — | — | US | disclosed |
| US-20230357261-A1 | ARYL HYDROCARBON RECEPTOR LIGANDS AND THEIR ANALOGUES FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISORDERS | The University of Pittsburgh- of the Commonwealth System of Higher Education | 2023-11-09 | — | — | US | disclosed |
| WO-2022061140-A1 | ARYL HYDROCARBON RECEPTOR LIGANDS AND THEIR ANALOGUES FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISORDERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2022-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357261-A1 | ARYL HYDROCARBON RECEPTOR LIGANDS AND THEIR ANALOGUES FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISORDERS | AHR, ARNT, MTNR1A | CYP2C9 1047/4885NPC1 2517/4885CYP1A2 237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.