Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2966316 | 0.83 | HSP90AA1 (0.57) | ALDH1A1MAPTKDM4EGFERGAA | |
| SCHEMBL2648963 | 0.83 | ALDH1A1 (0.61) | ALDH1A1MAPTKDM4EGFERGAA | |
| SCHEMBL2663969 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EGFERGAA | |
| SCHEMBL2664080 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EGFERGAA | |
| SCHEMBL18013115 | 0.77 | KEAP1 (0.46) | ALDH1A1MAPTKDM4EHTTMEN1 | |
| SCHEMBL4169639 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2AHSP90AA1 | |
| SCHEMBL8349593 | 0.75 | GAA (0.46) | ALDH1A1MAPTKDM4EGFERGAA | |
| SCHEMBL9072065 | 0.75 | GAA (0.50) | ALDH1A1MAPTKDM4EGAALMNA | |
| SCHEMBL1544647 | 0.74 | ALDH1A1 (0.70) | ALDH1A1MAPTKDM4EGFERGAA | |
| SCHEMBL23067374 | 0.73 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EGFERGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |