Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1833875 | 0.84 | TLR7 (0.36) | TLR7 | |
| SCHEMBL1254741 | 0.82 | TLR7 (0.51) | TLR7HASPINMAPTALDH1A1 | |
| SCHEMBL1829942 | 0.79 | HASPIN (0.44) | TLR7HASPINMAPTALDH1A1 | |
| SCHEMBL10074072 | 0.78 | HASPIN (0.40) | TLR7HASPINMAPTALDH1A1 | |
| SCHEMBL7480837 | 0.78 | TLR7 (0.43) | TLR7HASPINMAPTALDH1A1 | |
| SCHEMBL28429276 | 0.76 | TLR7 (0.34) | TLR7 | |
| SCHEMBL16019753 | 0.74 | TLR7 (0.47) | TLR7HASPINMAPTALDH1A1 | |
| SCHEMBL7564825 | 0.73 | TLR7 (0.47) | TLR7HASPINMAPTALDH1A1 | |
| SCHEMBL1760875 | 0.72 | KMT2A (0.46) | TLR7HASPINMAPTALDH1A1 | |
| SCHEMBL11780377 | 0.71 | MAPT (0.36) | TLR7MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213198-A1 | USE OF AROMATIC FUSED RING COMPOUND AS TREK-1 ACTIVATOR, AND PHARMACEUTICAL COMPOSITION AND ANALGESIC CONTAINING SAME | 华东师范大学 | 2023-11-09 | — | — | WO | disclosed |
| CN-117003756-A | Use of aromatic condensed-cyclic compounds as TREK-1 activators, pharmaceutical compositions containing same, analgesics | 华东师范大学 | 2023-11-07 | — | — | CN | disclosed |