Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1829942 | 0.95 | HASPIN (0.44) | TLR7HASPINSMN1; SMN2LMNAMAPT | |
| SCHEMBL1254741 | 0.89 | TLR7 (0.51) | TLR7HASPINSMN1; SMN2LMNAMAPT | |
| SCHEMBL10074072 | 0.82 | HASPIN (0.40) | TLR7HASPINSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL16019753 | 0.80 | TLR7 (0.47) | TLR7HASPINLMNAMAPTALDH1A1 | |
| SCHEMBL7564825 | 0.79 | TLR7 (0.47) | TLR7HASPINSMN1; SMN2LMNAMAPT | |
| SCHEMBL26640974 | 0.78 | TLR7 (0.39) | TLR7HASPINMAPTALDH1A1 | |
| SCHEMBL11679118 | 0.77 | PDE4A (0.38) | TLR7HASPINSMN1; SMN2LMNAMAPT | |
| SCHEMBL14889085 | 0.77 | TLR7 (0.45) | TLR7HASPINMAPTALDH1A1MAPK1 | |
| SCHEMBL22130771 | 0.77 | TLR7 (0.45) | TLR7HASPINSMN1; SMN2LMNAMAPT | |
| SCHEMBL11857075 | 0.76 | HASPIN (0.44) | HASPINSMN1; SMN2LMNANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840740-B1 | NEW INHIBITORS OF PLATELET AGGREGATION | ASTRAZENECA AB (SE) | 2002-05-02 | — | — | EP | disclosed |
| US-5747496-A | Inhibitors of platelet aggregation | ASTRA PHARMACEUTICALS LIMITED (GB) | 1998-05-05 | — | — | US | disclosed |