Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 11/20 | 0.59 |
| ▸ | CRBN | Q96SW2 | 11/20 | 0.59 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30643569 | 1.00 | DDB1 (0.59) | DDB1CRBNGPR119ALDH1A1LMNA | |
| SCHEMBL31134647 | 0.96 | DDB1 (0.59) | DDB1CRBNGPR119ALDH1A1LMNA | |
| SCHEMBL23301226 | 0.93 | DDB1 (0.67) | DDB1CRBNGPR119ALDH1A1LMNA | |
| SCHEMBL21876964 | 0.93 | DDB1 (0.67) | DDB1CRBNGPR119ALDH1A1LMNA | |
| SCHEMBL24480733 | 0.90 | GPR119 (0.62) | DDB1CRBNGPR119 | |
| SCHEMBL31062846 | 0.88 | DDB1 (0.59) | DDB1CRBNGPR119NAMPT | |
| SCHEMBL31726711 | 0.87 | DDB1 (0.60) | DDB1CRBNGPR119 | |
| SCHEMBL29680886 | 0.87 | DDB1 (0.60) | DDB1CRBNGPR119 | |
| SCHEMBL24670627 | 0.87 | DDB1 (0.58) | DDB1CRBNGPR119ALDH1A1LMNA | |
| SCHEMBL24671838 | 0.87 | DDB1 (0.58) | DDB1CRBNGPR119ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220640-A1 | CDK PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-11-16 | — | — | WO | disclosed |