Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 11/20 | 0.60 |
| ▸ | ADH1B | P00325 | 1/20 | 0.58 |
| ▸ | ADH1C | P00326 | 1/20 | 0.58 |
| ▸ | ADH1A | P07327 | 1/20 | 0.58 |
| ▸ | ADH7 | P40394 | 1/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14049932 | 0.91 | NR1H4 (0.61) | MEP1BADH1BADH1CADH1AADH7 | |
| SCHEMBL5992710 | 0.85 | ADH1B (0.52) | MEP1BADH1BADH1CADH1AADH7 | |
| SCHEMBL14049888 | 0.83 | FOLH1 (0.53) | MEP1BFOLH1HIF1ACA1CA2 | |
| SCHEMBL14049812 | 0.81 | NR1H4 (0.56) | MEP1BNR1H4 | |
| SCHEMBL8750958 | 0.81 | ADH1B (0.71) | ADH1BADH1CADH1AADH7 | |
| SCHEMBL14049806 | 0.80 | NR1H4 (0.47) | MEP1BNR1H4 | |
| SCHEMBL9201298 | 0.80 | ADH1B (0.50) | MEP1BADH1BADH1CADH1AADH7 | |
| SCHEMBL14049934 | 0.79 | PPARG (0.55) | ADH1BADH1CADH1AADH7NR1H4 | |
| SCHEMBL30444148 | 0.79 | MEP1B (0.65) | MEP1BFOLH1MRGPRX4HIF1ANR1H4 | |
| SCHEMBL16366609 | 0.79 | MEP1B (0.65) | MEP1BFOLH1MRGPRX4HIF1ANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022218379-A1 | SMALL-MOLECULE COMPOUND HAVING SUBSTITUTED PHENYL SPIRO[INDOLINE-3,3'-PYRROLIDINE] STRUCTURE | 中国科学院上海药物研究所 | 2022-10-20 | — | — | WO | disclosed |
| WO-2008127364-A2 | ANTIVIRAL COMPOUNDS AND USE THEREOF | MYRIAD GENETICS, INC. (US) | 2008-10-23 | — | — | WO | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |