SCHEMBL26643151

SCHEMBL26643151

O=C(O)c1ccc(/C=C/c2ccc3nonc3c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARA P10276 3/20 0.46
RARB P10826 3/20 0.46
RARG P13631 3/20 0.46
TTR P02766 2/20 0.44
ADORA3 P0DMS8 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA2B P29275 1/20 0.43
ADORA1 P30542 1/20 0.43
PDE4A P27815 1/20 0.43
PDE4B Q07343 1/20 0.43
PDE4C Q08493 1/20 0.43
PDE4D Q08499 1/20 0.43
GRIA3 P42263 1/20 0.43
GRIA4 P48058 1/20 0.43
ALDH1A1 P00352 1/20 0.43
FBP1 P09467 1/20 0.42
SRD5A1 P18405 1/20 0.42
SRD5A2 P31213 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL548490 0.81 GRIA3 (0.56) ADORA3ADORA2AADORA2BADORA1PDE4A
SCHEMBL5707470 0.80 IP6K1 (0.54) TTRALDH1A1MEN1KMT2AENPP2
SCHEMBL5707480 0.80 IP6K1 (0.54) TTRALDH1A1MEN1KMT2AENPP2
Hydrochloric Acid SCHEMBL562597 0.79 GRIA3 (0.54) ADORA3ADORA2AADORA2BADORA1PDE4A
SCHEMBL16687973 0.78 RARA (0.51) RARARARBRARGTTRALDH1A1
SCHEMBL9681086 0.76 ALDH1A1 (0.68) RARARARBRARGTTRALDH1A1
SCHEMBL9339856 0.76 ALDH1A1 (0.68) RARARARBRARGTTRALDH1A1
SCHEMBL2615887 0.76 ALDH1A1 (0.68) RARARARBRARGTTRALDH1A1
SCHEMBL69167 0.76 ALDH1A1 (0.68) RARARARBRARGTTRALDH1A1
SCHEMBL9681088 0.76 ALDH1A1 (0.68) RARARARBRARGTTRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313546-A1 NUCLEIC ACID BINDERS UNIVERSITY OF STRATHCLYDE (GB) 2025-10-09 US disclosed
EP-4522588-A1 NUCLEIC ACID BINDERS University of Strathclyde (GB) 2025-03-19 EP disclosed
CN-119585239-A Nucleic acid binding agents 斯特拉斯克莱德大学 2025-03-07 CN disclosed
WO-2023218194-A1 NUCLEIC ACID BINDERS UNIVERSITY OF STRATHCLYDE (GB) 2023-11-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313546-A1 NUCLEIC ACID BINDERS ZFR, NSUN3, POLI RARA 1311/4885RARB 1353/4885RARG 1536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.