Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 3/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RPA1 | P27694 | 1/20 | 0.37 |
| ▸ | MARS1 | P56192 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16114726 | 0.80 | ALDH1A1 (0.45) | MYCNR4A1ALDH1A1TSHRPOLB | |
| SCHEMBL1586432 | 0.80 | MYC (0.57) | MYCNR4A1ALDH1A1TP53CA1 | |
| SCHEMBL30644067 | 0.80 | MYC (0.57) | MYCNR4A1ALDH1A1TP53CA1 | |
| SCHEMBL26769876 | 0.77 | MAPK14 (0.39) | MYCNR4A1ALDH1A1LMNAKDM4E | |
| SCHEMBL19207007 | 0.76 | MYC (0.53) | MYCNR4A1ALDH1A1TP53CA1 | |
| SCHEMBL23354829 | 0.72 | RPA1 (0.53) | ALDH1A1SMN1; SMN2TSHRCASP1NOTUM | |
| SCHEMBL11403381 | 0.70 | MYC (0.57) | MYCNR4A1ALDH1A1TP53CA1 | |
| SCHEMBL23354803 | 0.70 | MARS1 (0.44) | MYCNR4A1SMN1; SMN2LMNARPA1 | |
| SCHEMBL26643209 | 0.70 | MYC (0.56) | MYCNR4A1ALDH1A1TP53CA1 | |
| SCHEMBL16655218 | 0.69 | MYC (0.51) | MYCNR4A1ALDH1A1TP53CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218023-A1 | THIAZOLOARYL-METHYL SUBSTITUTED CYCLIC HYDRAZINE-N-CARBOXAMIDE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-11-16 | — | — | WO | disclosed |