Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.35 |
| ▸ | EPOR | P19235 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5773300 | 0.81 | HTR2A (0.56) | HTR2AGRIK1GRIK2CTSC | |
| SCHEMBL5771311 | 0.81 | HTR2A (0.56) | HTR2AGRIK1GRIK2CTSC | |
| SCHEMBL20810341 | 0.76 | TLR8 (0.36) | HTR2AALDH1A1ALOX5ALOX5APPTGS1 | |
| SCHEMBL16243426 | 0.70 | NFE2L2 (0.38) | ALDH1A1NFE2L2 | |
| SCHEMBL23252588 | 0.69 | CNR2 (0.42) | ALDH1A1NFE2L2APP | |
| SCHEMBL31149192 | 0.68 | NFE2L2 (0.41) | HTR2ANFE2L2APP | |
| SCHEMBL13703292 | 0.68 | HDAC4 (0.41) | HTR2AGRIK1GRIK2EPORALDH1A1 | |
| SCHEMBL13703318 | 0.68 | HDAC4 (0.41) | HTR2AGRIK1GRIK2EPORALDH1A1 | |
| SCHEMBL16955931 | 0.67 | NFE2L2 (0.47) | MAPTPTGS1PTGS2NFE2L2 | |
| SCHEMBL15178223 | 0.67 | CETP (0.35) | HTR2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |