Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | CTSC | P53634 | 1/20 | 0.46 |
| ▸ | PAM | P19021 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5773300 | 1.00 | HTR2A (0.56) | HTR2ACTSCPAMGRIK1GRIK2 | |
| SCHEMBL6009944 | 0.82 | HTR2A (0.53) | HTR2APAMGRIK1GRIK2IDO1 | |
| SCHEMBL2664332 | 0.81 | HTR2A (0.38) | HTR2ACTSCGRIK1GRIK2 | |
| SCHEMBL26093212 | 0.81 | HTR2A (0.49) | HTR2AGRIK1GRIK2LMNATSHR | |
| SCHEMBL6286622 | 0.80 | HTR2A (0.60) | HTR2ACTSCPAMGRIK1GRIK2 | |
| SCHEMBL19604562 | 0.80 | HTR2A (0.66) | HTR2ACTSCPAMGRIK1GRIK2 | |
| SCHEMBL21189126 | 0.80 | HTR2A (0.66) | HTR2ACTSCPAMGRIK1GRIK2 | |
| SCHEMBL5475692 | 0.80 | HTR2A (0.66) | HTR2ACTSCPAMGRIK1GRIK2 | |
| SCHEMBL5475689 | 0.80 | HTR2A (0.66) | HTR2ACTSCPAMGRIK1GRIK2 | |
| SCHEMBL4029905 | 0.79 | HTR2A (0.59) | HTR2APAMGRIK1GRIK2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480988-A4 | REAGENTS FOR ASYMMETRIC ALLYLATION, ALDOL, AND TANDEM ALDOL AND ALLYLATION REACTIONS | UNIV COLUMBIA (US) | 2006-03-29 | — | — | EP | disclosed |
| EP-1480988-A1 | REAGENTS FOR ASYMMETRIC ALLYLATION, ALDOL, AND TANDEM ALDOL AND ALLYLATION REACTIONS | The Trustees of Columbia University in the City of New York (US) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003074534-A9 | REAGENTS FOR ASYMMETRIC ALLYLATION, ALDOL, AND TANDEM ALDOL AND ALLYLATION REACTIONS | UNIV COLUMBIA (US) | 2003-11-20 | — | — | WO | disclosed |
| WO-2003074534-A1 | REAGENTS FOR ASYMMETRIC ALLYLATION, ALDOL, AND TANDEM ALDOL AND ALLYLATION REACTIONS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2003-09-12 | — | — | WO | disclosed |