SCHEMBL2664360

SCHEMBL2664360

COc1cc(CNNC(=O)c2ccc(O)c(Cl)c2)cc(OC)c1OCc1ccc(OC(F)(F)F)cc1

nearest known ligand 0.74

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GCGR P47871 16/20 0.74
ADCYAP1R1 P41586 5/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2664243 0.85 GCGR (0.71) GCGRADCYAP1R1
SCHEMBL2663814 0.85 GCGR (1.00) GCGRADCYAP1R1
SCHEMBL9072211 0.83 GCGR (1.00) GCGRADCYAP1R1
SCHEMBL2664358 0.80 GCGR (0.69) GCGRADCYAP1R1
SCHEMBL7228854 0.75 GCGR (0.56) GCGR
SCHEMBL2664121 0.74 GCGR (0.80) GCGRADCYAP1R1
SCHEMBL2663822 0.74 GCGR (0.83) GCGRADCYAP1R1
SCHEMBL2663824 0.74 GCGR (0.83) GCGRADCYAP1R1
SCHEMBL2664352 0.72 GCGR (0.76) GCGRADCYAP1R1
SCHEMBL9072101 0.71 GCGR (0.75) GCGRADCYAP1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999001423-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 1999-01-14 WO disclosed