Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CHKA | P35790 | 2/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26644559 | 0.84 | PTGS2 (0.44) | MAPTKDM4EALDH1A1PTGS2CHKA | |
| SCHEMBL18102250 | 0.83 | KDM4A (0.42) | KMT2ARAD52RXFP1MAPTKDM4E | |
| SCHEMBL14392881 | 0.81 | KMT2A (0.37) | KMT2ARAD52RXFP1MAPTKDM4E | |
| SCHEMBL14392935 | 0.80 | KMT2A (0.40) | KMT2ARAD52RXFP1MAPTKDM4E | |
| SCHEMBL10104215 | 0.80 | KMT2A (0.36) | KMT2ARAD52RXFP1MAPTKDM4E | |
| SCHEMBL15460029 | 0.80 | KMT2A (0.36) | KMT2ARAD52RXFP1MAPTKDM4E | |
| SCHEMBL10104165 | 0.79 | KMT2A (0.39) | KMT2ARAD52RXFP1MAPTKDM4E | |
| SCHEMBL13989158 | 0.75 | KMT2A (0.49) | KMT2ARAD52RXFP1MAPTKDM4E | |
| SCHEMBL5679470 | 0.74 | CHAT (0.43) | KMT2ARAD52RXFP1MAPTKDM4E | |
| SCHEMBL13428293 | 0.74 | KMT2A (0.39) | KMT2ARAD52RXFP1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230341410-A1 | LUCIFERASE-BASED THERMAL SHIFT ASSAYS | PROMEGA CORPORATION | 2023-10-26 | — | — | US | disclosed |