Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645772 | 0.88 | GRM5 (0.51) | HTTALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL26645578 | 0.88 | GRM5 (0.50) | MEN1KMT2AGRM5NR1H2STS | |
| SCHEMBL16711314 | 0.88 | GRM5 (0.50) | HTTGRM5NR1H2 | |
| SCHEMBL26645099 | 0.86 | GRM5 (0.48) | HTTGRM5NR1H2GPR119STS | |
| SCHEMBL30622995 | 0.84 | CFTR (0.44) | HTTALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL26645025 | 0.84 | CFTR (0.44) | HTTALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL30622947 | 0.84 | CFTR (0.44) | HTTALDH1A1MEN1KMT2AGRM5 | |
| SCHEMBL26645632 | 0.84 | CFTR (0.44) | HTTALDH1A1MEN1KMT2AGRM5 | |
| SCHEMBL30623013 | 0.82 | GRM5 (0.45) | MEN1KMT2AGRM5NR1H2STS | |
| SCHEMBL26645489 | 0.82 | MEN1 (0.44) | MEN1KMT2AGRM5NR1H2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |