Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 2/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.42 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.42 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.42 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30623013 | 0.94 | GRM5 (0.45) | GRM5MEN1KMT2ASTSNR1H2 | |
| SCHEMBL30622973 | 0.89 | GRM5 (0.41) | GRM5MEN1KMT2ASTSNR1H2 | |
| SCHEMBL16711314 | 0.89 | GRM5 (0.50) | GRM5NR1H2 | |
| SCHEMBL26645030 | 0.88 | HTT (0.55) | GRM5MEN1KMT2ASTSNR1H2 | |
| SCHEMBL26645489 | 0.87 | MEN1 (0.44) | GRM5MEN1KMT2ANR1H2POLB | |
| SCHEMBL26645099 | 0.87 | GRM5 (0.48) | GRM5STSNR1H2 | |
| SCHEMBL26645758 | 0.86 | GRM5 (0.43) | GRM5MEN1KMT2ANR1H2POLB | |
| SCHEMBL30622947 | 0.85 | CFTR (0.44) | GRM5MEN1KMT2ANR1H2CACNB4 | |
| SCHEMBL26645632 | 0.85 | CFTR (0.44) | GRM5MEN1KMT2ANR1H2CACNB4 | |
| SCHEMBL26645345 | 0.85 | CYP3A4 (0.48) | GRM5MEN1KMT2ASTSNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |