Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 4/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645116 | 0.90 | CYP3A4 (0.45) | CSNK1DCSNK1EMEN1KMT2ADPP4 | |
| SCHEMBL26645098 | 0.89 | CYP3A4 (0.43) | CSNK1DCSNK1EMEN1KMT2ACYP3A4 | |
| SCHEMBL30622820 | 0.89 | CYP3A4 (0.43) | CSNK1DCSNK1EMEN1KMT2ACYP3A4 | |
| SCHEMBL26645283 | 0.89 | CSNK1D (0.40) | CSNK1DCSNK1EMEN1KMT2ADPP4 | |
| SCHEMBL26645019 | 0.88 | CSNK1D (0.47) | CSNK1DCSNK1EMEN1KMT2ACYP3A4 | |
| SCHEMBL26645394 | 0.86 | CSNK1D (0.42) | CSNK1DCSNK1EGPR119CKS1BSKP1 | |
| SCHEMBL26645443 | 0.86 | CSNK1E (0.43) | CSNK1DCSNK1EMEN1KMT2ACYP3A4 | |
| SCHEMBL30622922 | 0.86 | CSNK1E (0.43) | CSNK1DCSNK1EMEN1KMT2ACYP3A4 | |
| SCHEMBL26645805 | 0.85 | CSNK1E (0.42) | CSNK1DCSNK1EMEN1KMT2AGPR119 | |
| SCHEMBL26645619 | 0.85 | CSNK1D (0.44) | CSNK1DCSNK1EMEN1KMT2AGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |