Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.38 |
| ▸ | TACR3 | P29371 | 2/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645559 | 1.00 | GRM5 (0.39) | GRM5SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL26645526 | 0.88 | GRM5 (0.50) | GRM5MAPTTACR3SMO | |
| SCHEMBL26645151 | 0.88 | GRM5 (0.50) | GRM5MAPTTACR3SMO | |
| SCHEMBL26645036 | 0.85 | GRM5 (0.39) | GRM5SMO | |
| SCHEMBL26645490 | 0.85 | GRM5 (0.39) | GRM5SMO | |
| SCHEMBL30622912 | 0.84 | CACNB4 (0.39) | GRM5KDM4EHPGDHSD17B10TACR3 | |
| SCHEMBL30622811 | 0.84 | CACNB4 (0.39) | GRM5KDM4EHPGDHSD17B10TACR3 | |
| SCHEMBL26645253 | 0.75 | GRM5 (0.41) | GRM5 | |
| SCHEMBL26645161 | 0.75 | GRM5 (0.41) | GRM5 | |
| SCHEMBL26645248 | 0.75 | GRM5 (0.41) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |