Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNB4 | O00305 | 3/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 3/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 3/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 3/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.39 |
| ▸ | CACNG7 | P62955 | 3/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 3/20 | 0.39 |
| ▸ | CACNG1 | Q06432 | 3/20 | 0.39 |
| ▸ | CACNB2 | Q08289 | 3/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.39 |
| ▸ | CACNA1E | Q15878 | 3/20 | 0.39 |
| ▸ | CACNA2D4 | Q7Z3S7 | 3/20 | 0.39 |
| ▸ | CACNA2D3 | Q8IZS8 | 3/20 | 0.39 |
| ▸ | CACNG8 | Q8WXS5 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622811 | 1.00 | CACNB4 (0.39) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL30622961 | 0.89 | GRM5 (0.46) | SETD7HTTGRM5 | |
| SCHEMBL30622799 | 0.89 | GRM5 (0.46) | SETD7HTTGRM5 | |
| SCHEMBL30622977 | 0.88 | NR1H2 (0.41) | SETD7GRM5 | |
| SCHEMBL30623073 | 0.88 | NR1H2 (0.41) | SETD7GRM5 | |
| SCHEMBL26645559 | 0.84 | GRM5 (0.39) | GRM5TACR3KDM4EHPGDHSD17B10 | |
| SCHEMBL26645186 | 0.84 | GRM5 (0.39) | GRM5TACR3KDM4EHPGDHSD17B10 | |
| SCHEMBL26645578 | 0.79 | GRM5 (0.50) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL24321116 | 0.78 | GRM5 (0.37) | SETD7MEN1KMT2AGRM5 | |
| SCHEMBL30622984 | 0.78 | GRM5 (0.37) | SETD7MEN1KMT2AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |