Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.39 |
| ▸ | SMO | Q99835 | 2/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.35 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.35 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645490 | 1.00 | GRM5 (0.39) | GRM5SMOPDK1PDK2TRPV1 | |
| SCHEMBL26645151 | 0.87 | GRM5 (0.50) | GRM5SMOPDK1PDK2 | |
| SCHEMBL26645526 | 0.87 | GRM5 (0.50) | GRM5SMOPDK1PDK2 | |
| SCHEMBL30623073 | 0.86 | NR1H2 (0.41) | GRM5PDK1PDK2 | |
| SCHEMBL30622977 | 0.86 | NR1H2 (0.41) | GRM5PDK1PDK2 | |
| SCHEMBL26645559 | 0.85 | GRM5 (0.39) | GRM5SMO | |
| SCHEMBL26645186 | 0.85 | GRM5 (0.39) | GRM5SMO | |
| SCHEMBL26645434 | 0.77 | GRM5 (0.39) | GRM5SMOADORA3CHRNB2CHRNB4 | |
| SCHEMBL26645392 | 0.76 | SMO (0.43) | SMOTRPV1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL26645185 | 0.76 | SMO (0.43) | SMOTRPV1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |