Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | FRK | P42685 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 5/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.34 |
| ▸ | KRAS | P01116 | 2/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622301 | 1.00 | EGFR (0.38) | EGFRMAP4K4PRKACAFRKMAPK9 | |
| SCHEMBL30622336 | 1.00 | EGFR (0.38) | EGFRMAP4K4PRKACAFRKMAPK9 | |
| SCHEMBL30622374 | 0.86 | BCHE (0.39) | EGFRMAP4K4PRKACAFRKMAPK9 | |
| SCHEMBL26645237 | 0.86 | BCHE (0.39) | EGFRMAP4K4PRKACAFRKMAPK9 | |
| SCHEMBL26644950 | 0.85 | KRAS (0.35) | EGFRMAP4K4PRKACAFRKMAPK9 | |
| SCHEMBL30622327 | 0.85 | KRAS (0.35) | EGFRMAP4K4PRKACAFRKMAPK9 | |
| SCHEMBL26645397 | 0.84 | BCHE (0.41) | EGFRMAP4K4PRKACAFRKMAPK9 | |
| SCHEMBL26645712 | 0.83 | EGFR (0.37) | EGFRMAP4K4PRKACAFRKMAPK9 | |
| SCHEMBL30622978 | 0.79 | CYP3A4 (0.39) | EGFRMAP4K4PRKACAFRKMAPK9 | |
| SCHEMBL26644815 | 0.79 | BTK (0.39) | EGFRMAP4K4PRKACAFRKMAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |