Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | FRK | P42685 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | MARS1 | P56192 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.35 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645237 | 0.90 | BCHE (0.39) | BCHEMAP4K4EGFRPRKACAFRK | |
| SCHEMBL30622374 | 0.90 | BCHE (0.39) | BCHEMAP4K4EGFRPRKACAFRK | |
| SCHEMBL30622978 | 0.88 | CYP3A4 (0.39) | BCHEMAP4K4EGFRPRKACAFRK | |
| SCHEMBL26645503 | 0.85 | BCHE (0.40) | BCHEMAP4K4EGFRPRKACAFRK | |
| SCHEMBL26645162 | 0.85 | BCHE (0.40) | BCHEMAP4K4EGFRPRKACAFRK | |
| SCHEMBL30622992 | 0.85 | BCHE (0.40) | BCHEMAP4K4EGFRPRKACAFRK | |
| SCHEMBL26645286 | 0.84 | EGFR (0.38) | BCHEMAP4K4EGFRPRKACAFRK | |
| SCHEMBL30622301 | 0.84 | EGFR (0.38) | BCHEMAP4K4EGFRPRKACAFRK | |
| SCHEMBL30622336 | 0.84 | EGFR (0.38) | BCHEMAP4K4EGFRPRKACAFRK | |
| SCHEMBL26645193 | 0.83 | BCHE (0.39) | BCHEMAP4K4EGFRPRKACAFRK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |