Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | FRK | P42685 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645397 | 0.88 | BCHE (0.41) | BCHEMAP4K4EGFRPRKACAFRK | |
| SCHEMBL30622913 | 0.86 | BCHE (0.36) | CYP3A4CYP3A5USP30BCHEMAP4K4 | |
| SCHEMBL30622882 | 0.86 | BCHE (0.36) | CYP3A4CYP3A5USP30BCHEMAP4K4 | |
| SCHEMBL30622374 | 0.84 | BCHE (0.39) | BCHEMAP4K4EGFRPRKACAFRK | |
| SCHEMBL26645237 | 0.84 | BCHE (0.39) | BCHEMAP4K4EGFRPRKACAFRK | |
| SCHEMBL30622909 | 0.84 | RIPK3 (0.37) | CYP3A4CYP3A5USP30BCHEMAP4K4 | |
| SCHEMBL30622938 | 0.84 | RIPK3 (0.37) | CYP3A4CYP3A5USP30BCHEMAP4K4 | |
| SCHEMBL26645141 | 0.84 | RIPK3 (0.37) | CYP3A4CYP3A5USP30BCHEMAP4K4 | |
| SCHEMBL30622831 | 0.83 | MAPK14 (0.43) | EGFRCSNK1A1CSNK1DGPR119 | |
| SCHEMBL26645116 | 0.81 | CYP3A4 (0.45) | CYP3A4CYP3A5USP30BCHECSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |