Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 19/20 | 0.49 |
| ▸ | GSK3B | P49841 | 13/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.47 |
| ▸ | GSK3A | P49840 | 3/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622861 | 0.95 | MAPK14 (0.45) | MAPK14GSK3BMAPK8MAPK10GSK3A | |
| SCHEMBL26645020 | 0.92 | CSNK1E (0.45) | MAPK14GSK3BCSNK1DCSNK1E | |
| SCHEMBL30622893 | 0.87 | CSNK1E (0.41) | MAPK14GSK3BCSNK1DCSNK1E | |
| SCHEMBL26645300 | 0.86 | CSNK1E (0.43) | MAPK14MAPK8MAPK10CSNK1DCSNK1E | |
| SCHEMBL26644894 | 0.86 | MAPK14 (0.49) | MAPK14GSK3BMAPK8MAPK10GSK3A | |
| SCHEMBL26645795 | 0.85 | CSNK1E (0.47) | CSNK1DCSNK1E | |
| SCHEMBL24554208 | 0.85 | MAPK14 (0.56) | MAPK14GSK3BMAPK8MAPK10GSK3A | |
| SCHEMBL29682939 | 0.85 | MAPK14 (0.56) | MAPK14GSK3BMAPK8MAPK10GSK3A | |
| SCHEMBL24554177 | 0.85 | CSNK1E (0.45) | MAPK14MAPK8MAPK10CSNK1DCSNK1E | |
| SCHEMBL30579563 | 0.85 | CSNK1E (0.45) | MAPK14MAPK8MAPK10CSNK1DCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |