Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 7/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 6/20 | 0.45 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24554177 | 1.00 | CSNK1E (0.45) | CSNK1ECSNK1DRIPK3MAPK14GRIA1 | |
| SCHEMBL26645749 | 0.93 | CSNK1E (0.45) | CSNK1ECSNK1DRIPK3MAPK14NR3C2 | |
| SCHEMBL26645020 | 0.93 | CSNK1E (0.45) | CSNK1ECSNK1DRIPK3MAPK14GRIA1 | |
| SCHEMBL28875910 | 0.90 | RIPK3 (0.45) | CSNK1ECSNK1DRIPK3MAPK14MAPK10 | |
| SCHEMBL30622893 | 0.89 | CSNK1E (0.41) | CSNK1ECSNK1DRIPK3MAPK14GRIA1 | |
| SCHEMBL24553840 | 0.89 | MAPK14 (0.52) | CSNK1ECSNK1DMAPK14MAPK10MAPK13 | |
| SCHEMBL29683062 | 0.89 | MAPK14 (0.52) | CSNK1ECSNK1DMAPK14MAPK10MAPK13 | |
| SCHEMBL31680474 | 0.87 | RIPK3 (0.43) | CSNK1ECSNK1DRIPK3MAPK14NR3C2 | |
| 2-Aminopyridine SCHEMBL30623047 | 0.86 | CSNK1E (0.41) | CSNK1ECSNK1DRIPK3MAPK14NR3C2 | |
| SCHEMBL24553797 | 0.86 | CSNK1E (0.46) | CSNK1ECSNK1DMAPK14GRIA1CACNG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250276972-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | GRITSCIENCE BIOPHARMACEUTICALS CO LTD (CN) | 2025-09-04 | — | — | US | disclosed |
| CN-116744926-A | Compounds as inhibitors of casein kinase | 北京原基华毅生物科技有限公司 | 2023-09-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250276972-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | PACSIN2, CSNK1A1, CSNK1G3 | CSNK1E 4/4885CSNK1D 12/4885RIPK3 674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.