Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 10/20 | 0.48 |
| ▸ | BRAF | P15056 | 2/20 | 0.45 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 4/20 | 0.41 |
| ▸ | CDK8 | P49336 | 4/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.40 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622783 | 0.90 | GHSR (0.45) | GHSRBRAFCSNK1ECCNCCDK8 | |
| SCHEMBL26645778 | 0.90 | GHSR (0.45) | GHSRBRAFCSNK1ECCNCCDK8 | |
| SCHEMBL30622876 | 0.88 | GHSR (0.44) | GHSRBRAFCSNK1ECCNCCDK8 | |
| Hydrochloric Acid SCHEMBL26645017 | 0.81 | BRAF (0.47) | GHSRBRAFCSNK1ECCNCCDK8 | |
| Hydrochloric Acid SCHEMBL26645021 | 0.81 | BRAF (0.47) | GHSRBRAFCSNK1ECCNCCDK8 | |
| Hydrochloric Acid SCHEMBL30622810 | 0.81 | BRAF (0.47) | GHSRBRAFCSNK1ECCNCCDK8 | |
| SCHEMBL26645391 | 0.80 | MAPK14 (0.48) | BRAFCSNK1E | |
| SCHEMBL26645667 | 0.80 | BRD4 (0.39) | CREBBP | |
| SCHEMBL26645167 | 0.79 | SRC (0.43) | BRAF | |
| SCHEMBL26645255 | 0.74 | SMO (0.34) | GHSRCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |