Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622334 | 1.00 | EGFR (0.33) | EGFRMAPK1GHSRSIGMAR1BRD4 | |
| SCHEMBL30622397 | 0.93 | BRD4 (0.37) | EGFRMAPK1BRD4CREBBPBTK | |
| SCHEMBL30622384 | 0.93 | BRD4 (0.37) | EGFRMAPK1BRD4CREBBPBTK | |
| SCHEMBL26644821 | 0.93 | BRD4 (0.37) | EGFRMAPK1BRD4CREBBPBTK | |
| SCHEMBL26645478 | 0.90 | GHSR (0.33) | GHSRSIGMAR1BRD4CREBBP | |
| SCHEMBL26645535 | 0.87 | GHSR (0.31) | GHSRSIGMAR1BRD4CREBBP | |
| SCHEMBL30622323 | 0.87 | GHSR (0.31) | GHSRSIGMAR1BRD4CREBBP | |
| SCHEMBL30622347 | 0.87 | EGFR (0.35) | EGFRMAPK1GHSR | |
| SCHEMBL30622329 | 0.87 | TMEM97 (0.33) | EGFRMAPK1GHSRSIGMAR1BTK | |
| SCHEMBL26645120 | 0.87 | EGFR (0.35) | EGFRMAPK1GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |