Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
| ▸ | TACR3 | P29371 | 1/20 | 0.31 |
| ▸ | SMO | Q99835 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | BCL9 | O00512 | 1/20 | 0.30 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622334 | 0.90 | EGFR (0.33) | GHSRSIGMAR1BRD4CREBBP | |
| SCHEMBL26645769 | 0.90 | EGFR (0.33) | GHSRSIGMAR1BRD4CREBBP | |
| SCHEMBL26645535 | 0.89 | GHSR (0.31) | GHSRSIGMAR1BRD4CREBBP | |
| SCHEMBL30623066 | 0.88 | USP30 (0.33) | GHSRSIGMAR1BCL9CTNNB1 | |
| SCHEMBL26645209 | 0.86 | GHSR (0.33) | GHSR | |
| SCHEMBL26645143 | 0.86 | TMEM97 (0.35) | GHSRSIGMAR1 | |
| SCHEMBL26645626 | 0.85 | MAPK9 (0.40) | GHSRSMO | |
| SCHEMBL30622433 | 0.85 | JAK3 (0.31) | SIGMAR1 | |
| SCHEMBL26644840 | 0.85 | JAK3 (0.31) | SIGMAR1 | |
| SCHEMBL30622397 | 0.82 | BRD4 (0.37) | BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |