Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 1/20 | 0.46 |
| ▸ | GALR1 | P47211 | 1/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 3/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30623109 | 1.00 | GALR2 (0.46) | GALR2GALR1CSNK1ECSF1RCFTR | |
| SCHEMBL26645199 | 0.87 | JAK2 (0.43) | CSNK1EJAK2JAK1JAK3PTK2 | |
| SCHEMBL30622390 | 0.86 | CSNK1E (0.41) | CSNK1ECSF1RGSK3AGSK3BABCG2 | |
| SCHEMBL26644886 | 0.86 | CSNK1E (0.41) | CSNK1ECSF1RGSK3AGSK3BABCG2 | |
| SCHEMBL26645138 | 0.86 | GALR2 (0.48) | GALR2GALR1CSNK1ECFTRJAK2 | |
| SCHEMBL26645016 | 0.85 | CSNK1E (0.42) | GALR2GALR1CSNK1ECFTRCSNK1D | |
| SCHEMBL30622850 | 0.85 | CSNK1E (0.42) | GALR2GALR1CSNK1ECFTRCSNK1D | |
| SCHEMBL26645254 | 0.84 | MAPT (0.48) | CSNK1EJAK2JAK1JAK3PTK2 | |
| SCHEMBL26645230 | 0.83 | BUB1 (0.47) | CSNK1EJAK2JAK1JAK3CSNK1D | |
| SCHEMBL30622881 | 0.82 | CCNT1 (0.42) | GALR2GALR1JAK2JAK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |