Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 14/20 | 0.43 |
| ▸ | JAK1 | P23458 | 13/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645254 | 0.92 | MAPT (0.48) | JAK2JAK1CSNK1DCSNK1EJAK3 | |
| SCHEMBL26645230 | 0.90 | BUB1 (0.47) | JAK2JAK1CSNK1DCSNK1EJAK3 | |
| SCHEMBL30623109 | 0.87 | GALR2 (0.46) | JAK2JAK1CSNK1DCSNK1EJAK3 | |
| SCHEMBL26645791 | 0.87 | GALR2 (0.46) | JAK2JAK1CSNK1DCSNK1EJAK3 | |
| SCHEMBL26645681 | 0.85 | CSNK1E (0.48) | CSNK1DCSNK1E | |
| SCHEMBL26645058 | 0.84 | JAK2 (0.45) | JAK2JAK1CSNK1DCSNK1EJAK3 | |
| SCHEMBL26645524 | 0.83 | MKNK1 (0.52) | CSNK1DCSNK1EPRKCI | |
| SCHEMBL26645459 | 0.82 | CSNK1E (0.41) | CSNK1DCSNK1ECREBBPBRD4 | |
| SCHEMBL30623021 | 0.81 | CSNK1E (0.44) | CSNK1DCSNK1E | |
| SCHEMBL26645301 | 0.80 | CSNK1D (0.44) | CSNK1DCSNK1EPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |