Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31316087 | 1.00 | HTR1A (0.52) | HTR1ASLC6A4HTR2AHTR2CGRM4 | |
| SCHEMBL26646217 | 0.84 | SLC6A4 (0.43) | HTR1ASLC6A4HTR2AHTR2CGRM4 | |
| SCHEMBL31316098 | 0.84 | SLC6A4 (0.43) | HTR1ASLC6A4HTR2AHTR2CGRM4 | |
| SCHEMBL26646074 | 0.82 | SLC6A4 (0.41) | HTR1ASLC6A4HTR2AHTR2CGRM4 | |
| SCHEMBL31316021 | 0.82 | SLC6A4 (0.41) | HTR1ASLC6A4HTR2AHTR2CGRM4 | |
| SCHEMBL30600597 | 0.81 | HTR2A (0.63) | HTR1ASLC6A4HTR2AHTR2CFFAR2 | |
| SCHEMBL6636331 | 0.81 | HTR2A (0.67) | HTR1ASLC6A4HTR2AHTR2CADRB2 | |
| SCHEMBL30600702 | 0.80 | SLC6A4 (0.38) | HTR1ASLC6A4HTR2AHTR2CGRM4 | |
| SCHEMBL26646260 | 0.80 | SLC6A4 (0.38) | HTR1ASLC6A4HTR2AHTR2CGRM4 | |
| SCHEMBL31373456 | 0.80 | KCNH2 (0.50) | HTR1ASLC6A4HTR2AHTR2CGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4524135-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | Shanghai Apeiron Therapeutics Company Limited (CN) | 2025-03-19 | — | — | EP | disclosed |
| EP-4524136-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | Shanghai Apeiron Therapeutics Company Limited (CN) | 2025-03-19 | — | — | EP | disclosed |
| WO-2025036479-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2025-02-20 | — | — | WO | disclosed |
| WO-2023217232-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |
| WO-2023217230-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |