Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 10/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.35 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26646260 | 1.00 | SLC6A4 (0.38) | SLC6A4HTR2AHTR2CHTR1AGRM4 | |
| SCHEMBL31426965 | 0.86 | SLC6A4 (0.36) | SLC6A4HTR2AHTR2CHTR1AGRM4 | |
| SCHEMBL26646215 | 0.86 | SLC6A4 (0.36) | SLC6A4HTR2AHTR2CHTR1AGRM4 | |
| SCHEMBL31426931 | 0.84 | HTR1A (0.36) | SLC6A4HTR2AHTR2CHTR1AGRM4 | |
| SCHEMBL26646074 | 0.83 | SLC6A4 (0.41) | SLC6A4HTR2AHTR2CHTR1AGRM4 | |
| SCHEMBL31316021 | 0.83 | SLC6A4 (0.41) | SLC6A4HTR2AHTR2CHTR1AGRM4 | |
| SCHEMBL31316087 | 0.80 | HTR1A (0.52) | SLC6A4HTR2AHTR2CHTR1AGRM4 | |
| SCHEMBL26646337 | 0.80 | HTR1A (0.52) | SLC6A4HTR2AHTR2CHTR1AGRM4 | |
| SCHEMBL30600653 | 0.80 | KIF18A (0.39) | KIF18AFFAR2 | |
| SCHEMBL26646281 | 0.80 | KIF18A (0.39) | KIF18AFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4524136-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | Shanghai Apeiron Therapeutics Company Limited (CN) | 2025-03-19 | — | — | EP | disclosed |
| CN-119156382-A | Kinesin KIF18A inhibitor and application thereof | 上海湃隆生物科技有限公司 | 2024-12-17 | — | — | CN | disclosed |
| WO-2023217232-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |