Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.58 |
| ▸ | RAB9A | P51151 | 9/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | SLC34A2 | O95436 | 1/20 | 0.57 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.57 |
| ▸ | SLC34A3 | Q8N130 | 1/20 | 0.57 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.57 |
| ▸ | GUSB | P08236 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL273711 | 1.00 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2TDP1SLC34A2 | |
| SCHEMBL273866 | 0.91 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2TDP1GUSB | |
| SCHEMBL265497 | 0.91 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2TDP1GUSB | |
| SCHEMBL268762 | 0.90 | MAPT (0.54) | NPC1RAB9ASMN1; SMN2TDP1GUSB | |
| SCHEMBL273713 | 0.90 | MAPT (0.54) | NPC1RAB9ASMN1; SMN2TDP1GUSB | |
| SCHEMBL268120 | 0.89 | MEN1 (0.51) | NPC1RAB9ASMN1; SMN2TDP1SLC34A2 | |
| SCHEMBL273686 | 0.89 | MEN1 (0.51) | NPC1RAB9ASMN1; SMN2TDP1SLC34A2 | |
| SCHEMBL273716 | 0.88 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL266553 | 0.88 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL274846 | 0.87 | SLC34A2 (0.53) | NPC1RAB9ASMN1; SMN2TDP1SLC34A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134015-B2 | Compound inhibiting in vivo phosphorous transport and medicine containing the same | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-03-13 | — | — | US | disclosed |