SCHEMBL26650249

SCHEMBL26650249

CCN[C@@H](c1ccc(Br)cn1)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 1/20 0.37
RAB9A P51151 3/20 0.33
S1PR4 O95977 2/20 0.33
S1PR3 Q99500 2/20 0.33
ALDH1A1 P00352 3/20 0.31
NPC1 O15118 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26650250 1.00 GBA1 (0.37) GBA1RAB9AS1PR4S1PR3ALDH1A1
SCHEMBL31580571 0.84 TAAR1 (0.33) GBA1S1PR4S1PR3
SCHEMBL15240312 0.82 S1PR4 (0.35) GBA1S1PR4S1PR3ALDH1A1KDM4E
SCHEMBL26650065 0.82 S1PR4 (0.35) GBA1S1PR4S1PR3ALDH1A1KDM4E
SCHEMBL31391923 0.82 S1PR4 (0.35) GBA1S1PR4S1PR3ALDH1A1KDM4E
SCHEMBL31369209 0.82 S1PR4 (0.35) GBA1S1PR4S1PR3ALDH1A1KDM4E
SCHEMBL31580933 0.82 S1PR4 (0.31) S1PR4S1PR3
SCHEMBL31580941 0.82 ALDH1A1 (0.32) RAB9AS1PR4S1PR3ALDH1A1NPC1
Hydrochloric Acid SCHEMBL31580455 0.80 GBA1 (0.32) GBA1RAB9ANPC1
SCHEMBL31580589 0.80 RAB9A (0.32) RAB9AALDH1A1NPC1ATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4522596-A1 DIHYDROINDENE DERIVATIVES AS MALT1 INHIBITORS C4X Discovery Limited (GB) 2025-03-19 EP disclosed
WO-2023218203-A1 DIHYDROINDENE DERIVATIVES AS MALT1 INHIBITORS C4X DISCOVERY LIMITED (GB) 2023-11-16 WO disclosed