Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.72 |
| ▸ | BLM | P54132 | 1/20 | 0.72 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.72 |
| ▸ | F3 | P13726 | 3/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665062 | 1.00 | RAB9A (0.72) | RAB9AKMT2APOLBMEN1NPC1 | |
| SCHEMBL2647717 | 1.00 | RAB9A (0.72) | RAB9AKMT2APOLBMEN1NPC1 | |
| SCHEMBL2647718 | 1.00 | RAB9A (0.72) | RAB9AKMT2APOLBMEN1NPC1 | |
| SCHEMBL6918213 | 1.00 | RAB9A (0.72) | RAB9AKMT2APOLBMEN1NPC1 | |
| SCHEMBL25196615 | 0.94 | RAB9A (0.66) | RAB9AKMT2APOLBMEN1NPC1 | |
| SCHEMBL2664976 | 0.93 | MEN1 (0.65) | RAB9AKMT2APOLBMEN1NPC1 | |
| SCHEMBL2665098 | 0.93 | MAPT (0.67) | RAB9AKMT2APOLBMEN1NPC1 | |
| SCHEMBL2646972 | 0.93 | MAPT (0.67) | RAB9AKMT2APOLBMEN1NPC1 | |
| SCHEMBL2648111 | 0.93 | MEN1 (0.65) | RAB9AKMT2APOLBMEN1NPC1 | |
| SCHEMBL2665214 | 0.93 | MEN1 (0.65) | RAB9AKMT2APOLBMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |