Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.65 |
| ▸ | MAOB | P27338 | 7/20 | 0.60 |
| ▸ | MAOA | P21397 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2646972 | 1.00 | MAPT (0.67) | MAPTPOLBRAB9AMEN1KMT2A | |
| SCHEMBL2646975 | 1.00 | MAPT (0.67) | MAPTPOLBRAB9AMEN1KMT2A | |
| SCHEMBL2665062 | 0.93 | RAB9A (0.72) | MAPTPOLBRAB9AMEN1KMT2A | |
| SCHEMBL6918213 | 0.93 | RAB9A (0.72) | MAPTPOLBRAB9AMEN1KMT2A | |
| SCHEMBL2647717 | 0.93 | RAB9A (0.72) | MAPTPOLBRAB9AMEN1KMT2A | |
| SCHEMBL2647718 | 0.93 | RAB9A (0.72) | MAPTPOLBRAB9AMEN1KMT2A | |
| SCHEMBL2665069 | 0.93 | RAB9A (0.72) | MAPTPOLBRAB9AMEN1KMT2A | |
| SCHEMBL25196615 | 0.87 | RAB9A (0.66) | MAPTPOLBRAB9AMEN1KMT2A | |
| SCHEMBL2648111 | 0.86 | MEN1 (0.65) | MAPTPOLBRAB9AMEN1KMT2A | |
| SCHEMBL2665214 | 0.86 | MEN1 (0.65) | MAPTPOLBRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |