Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADCY6 | O43306 | 2/20 | 0.40 |
| ▸ | ADCY3 | O60266 | 2/20 | 0.40 |
| ▸ | ADCY9 | O60503 | 2/20 | 0.40 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.40 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.40 |
| ▸ | ADCY7 | P51828 | 2/20 | 0.40 |
| ▸ | ADCY2 | Q08462 | 2/20 | 0.40 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.40 |
| ▸ | ADCY4 | Q8NFM4 | 2/20 | 0.40 |
| ▸ | GIPR | P48546 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071502 | 0.85 | GCGR (0.51) | GCGRGIPR | |
| SCHEMBL6917344 | 0.84 | GCGR (0.58) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2665219 | 0.84 | GCGR (0.58) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL6917347 | 0.84 | GCGR (0.58) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2647008 | 0.84 | GCGR (0.51) | GCGRGIPR | |
| SCHEMBL2647002 | 0.84 | GCGR (0.51) | GCGRGIPR | |
| SCHEMBL9071390 | 0.84 | GCGR (0.42) | GCGRRAB9ANPC1SMN1; SMN2GIPR | |
| SCHEMBL2665119 | 0.84 | GCGR (0.51) | GCGRGIPR | |
| SCHEMBL2665067 | 0.83 | GCGR (0.55) | GCGRRAB9ALMNANPC1SMN1; SMN2 | |
| SCHEMBL2665036 | 0.83 | GCGR (0.53) | GCGRRAB9AGIPRACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |