Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 6/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | GIPR | P48546 | 2/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.37 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665135 | 0.98 | GCGR (0.47) | GCGRTRPV1MAPK14GIPRGPR139 | |
| SCHEMBL9071435 | 0.92 | GCGR (0.53) | GCGRTRPV1MAPK14GIPRTAOK1 | |
| SCHEMBL9071397 | 0.87 | GCGR (0.46) | GCGRTRPV1MAPK14GIPRNAMPT | |
| SCHEMBL2665131 | 0.86 | GCGR (0.46) | GCGRTRPV1MAPK14GIPRGPR139 | |
| SCHEMBL2664963 | 0.85 | GCGR (0.41) | GCGRMAPK14GIPR | |
| SCHEMBL9071398 | 0.85 | GCGR (0.46) | GCGRTRPV1MAPK14GIPRNAMPT | |
| SCHEMBL2664962 | 0.84 | GCGR (0.40) | GCGRMAPK14GIPR | |
| SCHEMBL2665121 | 0.84 | GCGR (0.51) | GCGRTRPV1MAPK14GIPR | |
| SCHEMBL2665086 | 0.83 | GCGR (0.48) | GCGRMAPK14GIPR | |
| SCHEMBL2665120 | 0.82 | GCGR (0.49) | GCGRTRPV1MAPK14GIPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |