Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 14/20 | 0.52 |
| ▸ | GIPR | P48546 | 5/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2655948 | 0.98 | GCGR (0.52) | GCGRGIPRTRPV1CYP3A4CYP2C8 | |
| SCHEMBL2655953 | 0.98 | GCGR (0.52) | GCGRGIPRTRPV1CYP3A4CYP2C8 | |
| SCHEMBL2647981 | 0.96 | GCGR (0.52) | GCGRGIPRTRPV1CYP3A4CYP2C8 | |
| SCHEMBL2647975 | 0.96 | GCGR (0.52) | GCGRGIPRTRPV1CYP3A4CYP2C8 | |
| SCHEMBL9071397 | 0.91 | GCGR (0.46) | GCGRGIPRTRPV1CYP3A4CYP2C8 | |
| SCHEMBL9071398 | 0.90 | GCGR (0.46) | GCGRGIPRTRPV1DHODH | |
| SCHEMBL2647916 | 0.88 | GCGR (0.53) | GCGRGIPRTRPV1CYP3A4CYP2C8 | |
| SCHEMBL2647920 | 0.88 | GCGR (0.53) | GCGRGIPRTRPV1CYP3A4CYP2C8 | |
| SCHEMBL9071435 | 0.86 | GCGR (0.53) | GCGRGIPRTRPV1DHODH | |
| SCHEMBL2665164 | 0.85 | GCGR (0.47) | GCGRGIPRDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |