Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 12/20 | 0.46 |
| ▸ | GIPR | P48546 | 5/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071398 | 0.98 | GCGR (0.46) | GCGRGIPRNAMPTTRPV1DHODH | |
| SCHEMBL2665225 | 0.91 | GCGR (0.52) | GCGRGIPRTRPV1DHODHCYP3A4 | |
| SCHEMBL2647975 | 0.91 | GCGR (0.52) | GCGRGIPRTRPV1DHODHCYP3A4 | |
| SCHEMBL2647981 | 0.91 | GCGR (0.52) | GCGRGIPRTRPV1DHODHCYP3A4 | |
| SCHEMBL2655948 | 0.90 | GCGR (0.52) | GCGRGIPRTRPV1DHODHCYP3A4 | |
| SCHEMBL2655953 | 0.90 | GCGR (0.52) | GCGRGIPRTRPV1DHODHCYP3A4 | |
| SCHEMBL6917434 | 0.88 | GCGR (0.50) | GCGRGIPRTRPV1CYP3A4CYP2C8 | |
| SCHEMBL2664934 | 0.88 | GCGR (0.50) | GCGRGIPRTRPV1CYP3A4CYP2C8 | |
| SCHEMBL2665137 | 0.87 | GCGR (0.47) | GCGRGIPRNAMPTTRPV1MAPK14 | |
| SCHEMBL2665161 | 0.85 | GCGR (0.51) | GCGRGIPRNAMPTCYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |