SCHEMBL2665164 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	GCGR	P47871	9/20	0.47

▸	GIPR	P48546	9/20	0.47

▸	PPARD	Q03181	1/20	0.47

▸	DHODH	Q02127	1/20	0.40

▸	EPHX2	P34913	1/20	0.39

▸	RHOC	P08134	2/20	0.39

▸	RHOA	P61586	2/20	0.39

▸	ALDH1A1	P00352	1/20	0.39

▸	DPP4	P27487	1/20	0.38

▸	CA1	P00915	1/20	0.37

▸	CA2	P00918	1/20	0.37

▸	GCG	P01275	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2665226	0.86	FABP4 (0.43)	GCGRGIPRALDH1A1
SCHEMBL2665086	0.85	GCGR (0.48)	GCGRGIPRPPARD
SCHEMBL2665225	0.85	GCGR (0.52)	GCGRGIPRDHODH
SCHEMBL2665222	0.85	KMT2A (0.41)	GCGRGIPREPHX2ALDH1A1
SCHEMBL2665224	0.84	GCGR (0.43)	GCGRGIPRALDH1A1
SCHEMBL2647975	0.84	GCGR (0.52)	GCGRGIPRDHODH
SCHEMBL2655953	0.84	GCGR (0.52)	GCGRGIPRDHODH
SCHEMBL2647981	0.84	GCGR (0.52)	GCGRGIPRDHODH
SCHEMBL2655948	0.84	GCGR (0.52)	GCGRGIPRDHODH
SCHEMBL2665228	0.84	GCGR (0.44)	GCGRGIPRPPARDEPHX2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2003048109-A1	NOVEL GLUCAGON ANTAGONISTS	NOVO NORDISK A/S (DK)	2003-06-12	—	—	WO	disclosed